The precise mechanisms driving tissue sculpting during morphogenesis remain a central question in developmental biology. We use zebrafish to study how cells acquire specific shapes, sizes, and polarities to form complex tissues like the epidermis and alimentary canal. Our lab utilizes state-of-the-art genetic, genomic, and microscopy approaches, including CRISPR-Cas9 and super-resolution imaging, to dissect the cellular processes and interactions that establish and maintain epithelial architecture.
